Acylcarnitines are essential for the transport of fatty acids into mitochondria for β-oxidation and for CoA homeostasis. They As a result deliver indirect evidence of altered mitochondrial metabolism (63) and suggest a dysfunction from the TCA cycle. Acylcarnitines and citrate have additional been demonstrated to modulate histone acetylation withi
Schematic representation of activated and inhibited Wnt/β-catenin pathway. “WNT ON condition�? On ligation of Wnts for their receptors composed of frizzled proteins and LRP5/6, the cytoplasmic protein DVL is activated and induces the suppression of GSK3β. Subsequently, stabilized β-catenin translocates in the nucleus and binds to TCF/LEF tra
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